HepaREF
Benchmark. Normalize. Translate.
A fully characterized human liver proteome reference standard for LC-MS proteomics-built to benchmark datasets, compare liver models, and improve confidence in translational research.
One reference. More comparable results.
Use HepaREF as a consistent human-liver benchmark across experiments, models, instruments, laboratories, and sites.
Characterized human liver proteome
Quantified Phase I/II enzymes, transporters, and key biomarkers.
Population-level context
Reference data helps place results within human population-level proteomic distributions.
Workflow-ready material
Compatible with LC-MS workflows and available as digested and undigested reagents.
A DEFINED QUANTITATIVE BENCHMARK
Anchor results in human liver biology
HepaREF provides characterized abundance data for important drug-metabolizing enzymes and transporters- giving teams a common point of comparison.
✓ Benchmark datasets and monitor analytical
performance
✓ Normalize across laboratories and multi-site studies
✓ Compare hepatocyte lots and advanced liver models
✓ Support IVIVE and PBPK model development
Where HepaREF fits
Designed for teams developing, evaluating, or translating human liver models and proteomic methods.
Validate and qualify in vitro liver models and NAMs
Improve IVIVE predictions and PBPK modeling
Standardize datasets across multi-site studies
Quantify enzymes, transporters, and relevant biomarkers
Support method development and performance monitoring
Study interindividual variability with human context
What You Receive with HepaREF
• HepaREF reference material
• Associated quantitative characterization data
• Certificate or supporting documentation
• Guidance for interpretation and use
• Access to PQ scientific support
See how HepaREF performs in your workflow.
Request an evaluation sample or speak with a Precision Quantomics scientist.
For research use only. Product specifications and claims should be confirmed before publication.