Revolutionize Your Drug Metabolism Research
Unlock the full potential of your drug metabolism research with our cutting-edge MSQ-CYP Assay Kit! Designed by Precision Quantomics, Inc., this revolutionary kit provides precise and reliable quantification of eleven key human cytochrome P450 (CYP450) enzymes involved in drug metabolism.
Key Features
• Comprehensive CYP450 Coverage: Quantify CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, and CYP3A5 in a single LCMS/MS assay.
• Validated SIL Peptides: Our kit includes a cocktail of validated stable isotope-labeled (SIL) surrogate peptides, ensuring accuracy and consistency.
• Ready for Targeted LC-MS/MS: Designed for targeted LC-MS/MS quantification using methods such as Selected Reaction Monitoring (SRM) or Parallel Reaction Monitoring (PRM).
• Dual Peptide Representation: Two surrogate peptides per enzyme provide robust and reliable quantification.
• High Sample Throughput: Designed to assay 96 samples, the kit is ideal for high-throughput research environments.
Applications in Drug Metabolism Research
1. CYP450 Enzyme Induction/Suppression Assays
2. Validate Novel In Vitro Models
3. Interindividual Variability: Assess variability in CYP450 enzymes across populations.
4. Relative Expression Factor (REF): Derive REF between recombinant CYP450 and human tissues for more accurate IVIVE predictions.
5. Differential Tissue Expression
Advantages of LC-MS/MS Proteomics using MSQ-CYP Assay Kit vs. Western Blotting
Special Offer and Additional Services
Precision Quantomics, Inc. not only provides the MSQ-CYP Assay Kit but also offers technology transfer to help implement the targeted LC-MS proteomics methodology on clients’ LC-MS instrumentation. Our current offer includes free method development consultation and reagents for the analysis of CYP450 enzymes in 6 samples.
Take your drug metabolism research to the next level with the MSQ-CYP Assay Kit from Precision Quantomics, Inc.
For more information and to place an order, visit our website or contact our sales team.