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Precision Quantomics

Enabling faster and safer drug development and pharmacotherapy

 
 

Explore Our Services

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Clinical assays and products to ensure safer and effective use of prescription drugs.

Diagnostic tests for disease risk prediction.

Quantitative and well-characterized in vitro tools for prediction of in vivo drug metabolism and transport.

Our Values

To create quantitative tools for precision medicine and accelerated drug screening and development

Clinical assays and products to ensure safer and effective use of prescription drugs.

Diagnostic tests for disease risk prediction.

Quantitative and well-characterized in vitro tools for prediction of in vivo drug metabolism and transport.

Our services include:

  • Protein quantification at femtomole to attomole levels from complex biological samples in humans and preclinical species
  • Targeted and global proteomics, specializing transmembrane proteins (drug metabolizing enzymes, transporters and receptors)
  • Quantitative and well-characterized in vitro tools for prediction of in vivo drug metabolism and transport
  • Clinical assays and products to ensure safer and effective use of prescription drugs
  • Diagnostic tests for disease risk prediction

At Precision Quantomics (PQ), we develop products and assays for quantitative pharmacology research to accelerate safer drug development and precision medicine.

The typical clients of PQ are pharmaceutical and biotech industry, academic laboratories, contract research organizations, biological reagent companies and diagnostic laboratories.

We strive for the development of cost effective, safe and efficacious drugs by delivering innovative tools to our clients that help to cure a wide range of diseases. We also provide tools for precision pharmacotherapy and disease diagnosis that enable clinicians to prevent and treat their patients with targeted interventions and precise drug dosing.

What We Do

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Precise protein quantification

    • By quantitative mass spectrometry approaches
    • In complex biological matrices
    • Using robust protocols for highest level of precision
    • Applicable to quantify proteins in small sample volumes (5 mg tissue and 50,000 cells)
    • At femtomole to attomole
    • Multiplexed analysis (3000-7000 proteins)
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Applications

    • Confirm protein levels in an induction assay
    • Characterize in vitro reagents for protein levels for accurate IVIVE and PBPK modeling
    • Confirm protein levels in inhouse generated recombinant proteins as compared to relevant in vivo levels
    • Interspecies differences in protein levels
    • Interindividual variability in protein levels, i.e., effect of age, genotype, sex, disease state/conditions
    • Global proteomics analysis to evaluate molecular perturbations in biological pathways
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Biological matrices

    • Cell culture samples
    • Tissues
    • Biofluids (blood, plasma, urine, CSF)
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Custom support, consulting, and training

    • Method development for quantification of any protein or set of proteins
    • Selection of surrogate peptides for targeted proteomics analysis
    • Custom synthesis of surrogate peptide kits for protein quantification

Contact Our Team

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